Acute Coronary Syndromes, Third Edition by Eric Topol

By Eric Topol

With precise contributions from forty five well known overseas specialists, this 3rd variation stands by myself because the so much accomplished, modern view of the biology, body structure, and administration of acute coronary syndromes (ACS)-offering 32 chapters that span the state-of-the technological know-how within the box and supply fascinating discussions on CRP and different sickness markers, microcirculation, stem cellphone remedy, and the improvement of specialised facilities for ACS therapy.

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Adhesion molecules i n inflammatory diseases. Drugs 1998;56:977-988. Petruzzelli L. Takami M, Humes HD. Structure and function of cell adhesion molecules. Am J Med 1999;106:467-476. Frenette PS, Wagner DD. Adhesion molecules-part 1. N Engl J Med 1996; 334:1526-1529. Frenette PS, Wagner DD. Adhesion molecules-part 11: bloodvessels and blood cells. N Engl J Med 1996;335:43-45. Springer TA. Adhesionreceptorsof the Inununesystem. Nature 1990;346: 425-434. Braun M, Pietsch P. Schror K, Baurnann G. Felix SB.

39. 40. 41. 42. 43. ical analysis of the cellular composition ofhunml atherosclerotic lesions. Am J Pathol1986:125:191-207. SchInitz G, Herr AS, Rothe G. T-lymphocytes and monocytes in atherogcnesis. Herz 1998:23: 168- 177. FrankenbergerM,Sternsdorf T, PechumerH, Pforte A,Ziegler-Heitbrock HW. Differential cytokine expression in human blood monocyte subpopulations: a polymerase chain reaction analysis. Blood 1996:87:373-377. Boyle JJ. Association 0 1 coronary plaque rupture and atherosclerotic infammation.

In fact, these studiesshow that the greater the degree of luminal stenosis a plaquc causes, the lower the circunferential wall stress it will experience. Aside from increases in the thrombogenic potential of platelets. adrenergic stimulation produced by awakening or by triggering events modeled by the Northridge earthquake could change the local hemodynamics in the coronarycirculation, and thus the forces brought to bear on a potentially unstable plaque (8). Similar to Laplace’s law, the circumferential wall stress varies directly with the luminal pressure.

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