ABC of Transfusion (ABC Series) by Marcela Contreras

By Marcela Contreras

Blood providers and Transfusion medication became extra medical, medical, good organised and consolidated over the past twenty years. extra is understood concerning the frequency and aetiology of the risks of blood transfusions. The ABC of Transfusion is a good demonstrated creation for all employees operating in blood companies, blood transfusion departments, surgical devices and in depth care, and all prescribers and clients of blood. it's a complete, very popular consultant to all of the sensible points of blood transfusion, together with a number of the issues which may arise.This fourth variation of ABC of Transfusion comprises 5 new chapters on the entire most recent matters together with pre-transfusion trying out, vCJD, stem cellphone transplantation, immunotherapy, and acceptable use of blood - reflecting the truth that transfusion drugs has been revolutionised. invaluable as a realistic consultant, a refresher or for speedy reference, it covers all crucial transfusion concerns and is a perfect resource of data for all health and wellbeing execs concerned with secure and effective use of blood.

Show description

Read or Download ABC of Transfusion (ABC Series) PDF

Best hematology books


Thrombopoielin (TPO) is the main regulator of platelet construction and is produced constilulively through the hepatocyte. it's secreted into the move the place it's more often than not certain and got rid of via thrombopoielin receptors (c-mpl) on platelets and megakaryocytes. the rest thrombopoielin within the flow regulates the expansion of bone marrow megakaryocytes and the creation of platelets.

Hodgkin Lymphoma

The definitive textual content on Hodgkin lymphoma is now in its completely revised, up to date moment version. greater than a hundred famous experts from all elements of the area supply complete, present details on each point of Hodgkin lymphoma, together with etiology, epidemiology, biology, pathology, overview, staging, remedy, and follow-up.

Artificial Cells: Biotechnology, Nanomedicine, Regenerative Medicine, Blood Substitutes, Bioencapsulation, and Cell Stem Cell Therapy (Regenerative Medicine, Artificial Cells and Nanomedicine)

This can be the 1st e-book that offers a finished overview of the full sector of man-made cells. the writer, a pioneer of the sector, invented the 1st synthetic cells a few 50 years in the past and has persisted to hold out lively learn during this box. given that then, there were explosive learn actions world wide on man made cells, particularly in fields with regards to biotechnology, nanomedicine, mobile treatment, blood substitutes, drug supply and others.

Transfusion in the Intensive Care Unit

As a result of a excessive occurrence of anemia, seriously sick sufferers are often transfused, with as much as forty% of sufferers receiving a transfusion in the course of their remain within the extensive Care Unit. It has develop into more and more transparent that there's an organization among transfusion and hostile results, underlining the necessity for a cautious overview of the hazards and advantages of a blood transfusion.

Additional info for ABC of Transfusion (ABC Series)

Example text

Furthermore, pulmonary infiltration may result in serious morbidity following granulocyte transfusions. Pulmonary infiltration results from antibody-mediated sequestration of white cells in the lungs and presents clinically with fluid overload, pulmonary oedema and exacerbation of pre-existing pulmonary pathology. In the most severe form, the adult respiratory distress syndrome may ensue and patients may require ventilatory and/or cardiovascular support. The development of HLA or HNA alloimmunization in immunosupressed patients receiving granulocytes transfusion is not a common event.

Thrombocytopenia may be the direct consequence of bone marrow infiltration (for example, acute leukaemia), of bone marrow failure due to disease (aplastic anaemia) or of treatment with cytotoxic agents. Platelet transfusions have made potentially curative intensive cytotoxic treatment regimens, with or without stem cell transplantation, possible. Interest in the use of granulocyte transfusions has been renewed due to the increase in numbers of patients with (or at high risk of) fungal infections arising from periods of prolonged neutropenia following more intensive chemotherapy regimens.

Adverse effects of platelet transfusions Most of the adverse effects common to other blood components may also occur following platelet transfusions (see Chapters 11–13). The most common adverse effect of platelet transfusion is the development of immunological reactions such as non-haemolytic febrile transfusion reactions (NHFTRs). Febrile reactions can be caused by white cell antibodies, mainly HLAs, present in the recipient 25 and reacting with donor leucocytes, or, rarely, by interleukins and tumour necrosis factor released by leucocytes present in the platelet concentrate during storage.

Download PDF sample

Rated 4.64 of 5 – based on 13 votes